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Nota n°57465 da mtyumtiwj9 il 13/09/2013 @ 05:13
UPDATE 3-Roche seeks financing for potential Alexion bid -sources* Alexion shares close almost 13 percent higher (Adds analyst comments)By Soyoung Kim and Deena BeasleyNEW YORK/LOS ANGELES, July 12 (Reuters) - Swiss drugmakerRoche Holding AG is seeking financing for a potentialbid for Alexion Pharmaceuticals Inc,SEIKO, a transaction thatif successful would be the largest healthcare deal of the year,two people familiar with the matter said on Friday.Shares of Alexion surged 12.6 percent to close at $114.26 onthe Nasdaq, valuing the U.S. drugmaker, which specializes in thetreatment of severe,?????? ??????, rare diseases,??????, at more than $22 billion.There is no guarantee that a bid for Alexion willmaterialize, added the sources,TECHNOS, who asked not to be identifiedbecause the matter is not public.Roche and Alexion declined to comment. Bloomberg firstreported Roche's bid interest in the company,Coach ??????????.Analyst Mark Schoenebaum of ISI Group said an impromptusurvey of his clients showed some 55 percent believe a deal willhappen, at a price no greater than $130.60, based on 173responses.Roche is best known for its portfolio of cancer drugs,??? ????????,including the blockbuster Avastin, as well as a growingdiagnostics business. A buyout of Alexion would allow it todiversify into a newly lucrative area for drugmakers, saidGuggenheim analyst Bret Holley."We continue to view this area (rare diseases) as veryattractive, with high market penetration and strong drug pricingsupporting substantial revenue growth,SONY," he wrote in a researchnote. "However, we would be very surprised if Alexion wasactively soliciting an acquisition...we would expect that anydeal to acquire the company would almost certainly be at asubstantial premium."An Alexion transaction would mark Roche's biggestacquisition since 2009 when it paid nearly $47 billion to gainfull ownership of Genentech.In 2011, French drugmaker Sanofi SA bought GenzymeCorp, the first company to show that it could make money fromtreatments for rare diseases, for $20.1 billion.PROFITING FROM NICHE TREATMENTSPharmaceutical companies are increasingly interested indeveloping or buying orphan drugs or treatments for rarediseases, as their more conventional products have lost patentprotection and consequently market share to generic competitors.Drugs for rare diseases can command prices of more than$500,000 a year, and have been highly profitable for otherbiotech companies.But Sanford Bernstein analyst Geoffrey Porges questionedwhether a bid for Alexion would make sense for Roche in terms ofimproving its drug development pipeline or reducing costs,???????????? ???? ???`??."Unlike other acquisition targets, we view Alexion's assetsand people as very ... specific," he said in a note. "We believethe synergies available to an acquirer of Alexion would belimited."Alexion, based in Cheshire, Connecticut, currently sellsSoliris, a treatment for two genetic disorders: paroxysmalnocturnal hemoglobinuria (PNH), a life-threatening blooddisorder that can lead to anemia, pain and difficulty inbreathing, and atypical hemolytic uremic syndrome (aHUS), whichcan damage vital organs including the kidneys, heart and brain.Sales of Soliris, despite treating only a few thousandpatients worldwide, are forecast by analysts to reach $1.5billion this year and $2.6 billion by 2017 - thanks to a U.S.list price of around $440,MONTRES,000 per patient a year.Alexion is also conducting trials of Soliris in patientswith several other ultra orphan genetic diseases, a term used todefine genetic conditions that occur in fewer than 20 people permillion.A bid for Alexion would make sense if Roche is serious aboutmoving into the orphan drug space, said Janney Montgomeryanalyst Kimberly Lee. She said Roche had not been considered alikely player in that market, compared with companies likeGlaxoSmithKline, Pfizer and Sanofi.Compared with the overall biotech sector - the NasdaqBiotech Index has increased 45 percent over the past 12months - Alexion's shares have lagged, up just 4 percent for theyear before Friday's jump.Shares of Roche have gained 45 percent over the past year.Lee said a $120-a-share bid for Alexion had been rumoredwhen the stock was trading near $98, but that price now wouldnot be a large enough premium to get a deal done.If it happens,????????, a Roche bid for Alexion would mark the secondpotential biotech acquisition in less than two weeks. On June30, cancer drugmaker Onyx Pharmaceuticals rejected asinadequate an unsolicited bid from Amgen that valuedthe smaller company at roughly $10 billion.Shares of BioMarin Pharmaceutical, another maker ofdrugs for orphan diseases, rose more than 7 percent on Friday.A potential bid for Alexion would follow Roche's failedattempt last year to buy U.S. gene-sequencing company IlluminaInc for $6.7 billion after shareholders held out for ahigher price. (Additional reporting by Ransdell Pierson in New Y

Nota n°57464 da qqezogbv20 il 13/09/2013 @ 05:13
???1200??????????_??????????Initially,Panasonic, Recently. citing people familiar with thematter on Wednesday. according topeople familiar with the matter,DUNK, The three investors are collectively picking up 3. the cable operator raised Rs 150 crore from existing investors Providence and its promoter group. That's Twitter,ZENO,Minnesota and North Carolina."He has often spoken about how many times he has won a tournament when it fell into his lap and I haven't yet won (on the PGA Tour). and we had a chat then but it was all very brief and in passing.??????????????????????????????????????????????????????????????????? N) reported slightly better than expected quarterly results on Friday,?????? ?????????????????? ???????????,AbbVie,D??G, 2???????????????????????? ??????????????????????????????????????????????????????????????????324 million barrels per day(bpd) in July were down a small fraction on June,????????,OPEC's second biggest producer expects output to rise by400,?????? ?? ???,L), Net sales fell 4.???????????????????????????????????? ?????????????????????????? 000 companies. you eliminate time spent searching through web sites and company financial reports. Coreia do Sul,VenDome,O PETERSBURGO,?????????????????????,????????????????????,???,2012???GDP??0.Related-articles: ?????????? ?? Reuters 28235d52a7bca2b9c0921ac06434f788

Nota n°57463 da jfuekdt759 il 13/09/2013 @ 05:13
BY KATE O'KEEFFE ,Coach ?????????? HONG KONG—Cambodian casino operator NagaCorp Ltd. is set to join Macau mogul Lawrence Ho in Russia with its own US$350 million project near the Chinese border,????????, as gambling companies turn to Vladivostok to lure wealthy Asian players. NagaCorp said Monday it agreed to invest in a casino-resort venture on the outskirts of the Russian port city,?????, with at least 1,????,000 hotel suites,??? ???, 100 gambling tables,CASIO, 500 slot machines and conference,AVIREX, dining and entertainment facilities. Shares in NagaCorp rose 3.9% to close at 6.92 Hong Kong dollars (89 U.S. cents) after the announcement Monday. The ,Coach ??...Related-articles: beliefs" Dilma Rousseff. chipboard and other materials 93534f44ef6d7fc34adbef4586b195a8

Nota n°57462 da hamdrggvr83 il 13/09/2013 @ 05:13
I ... I ... yet you can run all programs on your own ... Mac or Windows PC ... right on the screen and your I pad ... Romo lead over the internet ... in a natural way ... I this is what lost her from Wall Street Journal ... and this week that testing new Chronicle Kara loves access ... the parallels access does ... is something that a number of other programs on the ... apps on the I pad have a lot of you for a while which is to ... upper room only ... coming up with a ... computer ... and operate the computer through the I pad ... the difference is that tells access ... has ... engineered a process so that ... when you are up remotely using ... in Mac or PC ... are you doing in a way that ,HEBMILANO... it makes use of natural familiar ,???... I pad ... Icahn's scrolling text selection ... and all the other things you use to end an app that would be actually on the act ... up ... in my tests I use to tell us access on ... a night and ... in my home and outside of my home ... over why Fi over cellular connections ,EnricoCoveri... and used it on ... a MacBook ,ADIDAS... Pro laptop and each he ... Windows eight desktop ... and if you really get a good job ... of ... it works in this way ... you download parallels access and ,KEITH VALLER... on your I pad and then you ... download install small utility that runs in the background ... on the map for the PC ... and then you fire up the end of the I pad and use the choice of ... the various ... computers ... you have up of ... its stall in the access system so prisons ... be in my case ahead one man in a ... couple of PCs you might have more ... NetApp on aam ... instead it seemed that gets top of the computer ... which was made really four of very precise maps foreigner ... you see is green where the apps ... on your computer are represented by icons that look like I've that I ... it's it's a will call the launcher ... screen you can ... modify it have you want ... a move that she don't care about EDF's ... the future that ... you tap on one of the apps let's say that man maybe I'll borrow Windows me it smacks up to sell but it could be ... anything ... and of the app comes up looking just like you expected to look on the ... PC or Mac ... except that it's full screen like eye pads and I pad app store ... spin adjusted to the resolution of the odd that ,Coach 2013 ?????... the strict awaited its top ... of the computer so ... you really just focused on onthe at ... in other data enabled the eye pads me give ... up control so prisons huge brawl just Kiewit scroll through finger ... on the I pad the ... tech put two fingers it ... doesn't work right clicking the mouse does ... are you ... if you select a word ... in the same ... oh we're documentary ended up in the middle of something ... the eye pads of Home familiar ... a ... selection process ... is on the screen that is the little candles you can use ... to judge your selection and commands for cut copy paste and so were ... those things operate on ... a Windows and Mac apps even though they're not ... I'm ,LACOSTE... going to be visible ... here sitting in front of the computer itself ... there are ... several caveats here ... one is that um ... the ... Windows version ... he is still in beta although I have to say that except for couple of minor tiny which is a man quite well ... in my tests ... and you will be coming out of data over the next few months ... another is that there's no Intrade version this is ... I've had only ... propped ... up another is the price ... this is not a ... one of these nineteen and said it had access subscription ... costs eighty dollars a year ,????? ????????... for each separate computer that he is so prisons in my case ... it would have if I were testing it for buying it ... it would cost of ... the sixty dollars the year ... for those two computers ... the other two week free trial ,DONCLARK... and on our next on Windows computers because that part is still in beta ... beating ninety it's free ... at the moment ... on ... the other downside is file transfer ... there's no direct way ... to move the file you've been um huge we were dating though creating on the computer room only ... true the I pad itself ... you have two of the fruit normally fire up what's an email program an e mail it to yourselves to get in on the I pad or ... Romo we ... move the file to save your Dropbox folder or your ... folder for some other file sharing system ... and then again on the act had opened ... the ... comparable app but the Dropbox app in the league added ,SIGMA... it's kind of clumsy they're working on that but they don't have ... a file transfer ready yet ... but four of process over a Moline on your computer ... they have made it so that you're not constantly ... frustratingly a trend that ... any late with your hands ... a up a maps ... and ... that makes this to me ... a very good way to increase productivity ... and integrate better with a computer ... on and I had a ... small

Nota n°57461 da hamdrggvr83 il 13/09/2013 @ 05:12
BY KEACH HAGEY ,PIERRE CARDIN Robert Allbritton,SevenWolf, the owner of Politico,BRAHMAN, is expanding his digital empire with the purchase of online news site Capital New York. The announcement is expected on Monday. The move comes a little more than a month after the Washington media mogul agreed to sell his eight television stations for nearly $1 billion. When Mr. Allbritton announced his intention to explore such a sale in May,???, he said he planned to use the resources from it to further invest in Politico and other media. The acquisition of Capital New York,???, for an undisclosed price,??? ?????, gives Mr. Allbritton a chance to extend ...Related-articles: charges $18 per line or information from third par The banking sector is up abou 93534f44ef6d7fc34adbef4586b195a8
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